The primary aim is to facilitate an overall well-being for patients suffering from incurable neurological disorders through Neuroregenerative Rehabilitative Therapy (NRRT). In addition to the above, providing support to cellular therapy research & regenerative medicine and increasing awareness about its applications are supplementary objectives.
In the past donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: They can grow into specialized cell types such as nerve cells, muscle cells, and blood cells.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated A? clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read extra details on NeuroGen Hospital.
Considerations Before Starting Treatment: The needs of a child with cerebral palsy aren’t solely based on correcting their physical disabilities. There are also social and emotional aspects of living a more fulfilling life. These aspects shouldn’t be ignored when considering treatment and therapy. Many children are content with their disabilities. As a parent, it’s important to consider their feelings. Some treatments can be stressful and uncomfortable, and may not be in the best interest of the child. It’s important to discuss the physical and emotional impacts of all treatments with specialists and most importantly, the child.
A few tricks to help your child with autism: ADS support groups – Joining an ASD support group is a great way to meet other families dealing with the same challenges you are. Parents can share information, get advice, and lean on each other for emotional support. Just being around others in the same boat and sharing their experience can go a long way toward reducing the isolation many parents feel after receiving a child’s diagnosis. Respite care – Every parent needs a break now and again. And for parents coping with the added stress of ASD, this is especially true. In respite care, another caregiver takes over temporarily, giving you a break for a few hours, days, or even weeks. Individual, marital, or family counseling – If stress, anxiety, or depression is getting to you, you may want to see a therapist of your own. Therapy is a safe place where you can talk honestly about everything you’re feeling-the good, the bad, and the ugly. Marriage or family therapy can also help you work out problems that the challenges of life with an autistic child are causing in your spousal relationship or with other family members.
The spinal cord is responsible for sending messages from the brain to all parts of the body. It also sends messages from the body to the brain. We’re able to perceive pain and move our limbs because of messages sent through the spinal cord. If the spinal cord sustains an injury, some or all of these impulses may not be able to “get through.” The result is a complete or total loss of sensation and mobility below the injury. A spinal cord injury closer to the neck will typically cause paralysis throughout a larger part of the body than one in the lower back area.
Stem Cells: So far, umbilical cord blood has been successfully used in the treatment of over 75 conditions, such as various types of cancer, blood disease and immune deficiencies, such as leukemia, sickle cell anemia (siclemia), thalassemia, Hodgkin’s disease and non-Hodgkin’s lymphoma. Stem cells also treat very rare, potentially fatal conditions, such as Krabbe’s disease or Sanfilippo’s syndrome. But from year to year new diseases appear on the list of 75 that can be treated with the help of stem cells.
Stem Cell Therapy has a promising potential to transmit progressive muscle proteins and restore the stem pool, thus, being the right muscular dystrophy treatment in India approach due to MD’s for deteriorative nature. Stem cells have the capacity to convert into any type of body cell and undergo self regeneration. The capacity of adult muscle to undertake renewal is largely credited to a distinctive subpopulation of muscle cells, called satellite cells. These cells are believed to be the chief cell type associated with skeletal muscle regeneration. Muscular dystrophy can wear out the emotional, physical and ?nancial condition of the patients, as well as their caregivers. Cell therapy for muscular dystrophy in India at NeuroGen Hospital has come up as a successful treatment option after years of research and study. This is an incredible leap for not just muscular dystrophy treatment in India, but also the world! See more details Stem Cell Treatment For Muscular Dystrophy.